Neurofibromatosis with pathological fractures in the newborn.

Neurofibromatosis may be recognized in childhood, though it is unusual for the full syndrome to be present at an early age. Thus skin pigmentation may be the only manifestation in infancy, later to be followed by the development of skin tumours, skeletal and other abnormalities. The following case of neurofibromatosis is of interest in that it occurred in a newborn infant who presented with skin pigmentation, bowing of the legs, pathological fractures, cardiac irregularity, and enlargement of the clitoris.